Denali Therapeutics Inc. (DNLI)
$
13.16
-1.03 (-7.83%)
Key metrics
Financial statements
Free cash flow per share
-2.1461
Market cap
1.9 Billion
Price to sales ratio
0
Debt to equity
0.0453
Current ratio
10.2651
Income quality
0.7298
Average inventory
0
ROE
-0.4079
Technology
Technology – consumer electronics
Largecap
With a market cap of 121,78 bil stock is ranked 1
Low risk
ISS score of this stock is ranked 1
Company description
Profile
Denali Therapeutics Inc. is a biopharmaceutical company focused on the discovery and development of therapeutic candidates for neurodegenerative diseases based in the United States. The company recorded a notable revenue of $0.00 showcasing its steady growth in a challenging industry. The earnings per share (EPS) is reported at -$2.57 indicating the company's profitability on a per-share basis, despite facing operational challenges. Its operating expenses amount to $501,878,000.00 encompassing various operational costs incurred during development. The EBITDA ratio is 0.00 highlighting the company's operational efficiency in its ongoing and future projects. However, the company reported a net loss of -$422,773,000.00 indicating challenges in its operations as it continues to invest in innovative therapies. Denali offers a range of therapeutic candidates, such as the LRRK2 inhibitor product candidate BIIB122/DNL151, which is currently in phase I and phase Ib clinical trials for the treatment of Parkinson's disease. Additionally, the company is progressing with DNL310 in Phase I/II trials for Hunter syndrome, and DNL343 in phase 1 trials for amyotrophic lateral sclerosis (ALS). Completing a phase I clinical trial, AR443820/DNL788 targets ALS, multiple sclerosis (MS), and Alzheimer's disease, while SAR443122/DNL758 is in phase II trials for cutaneous lupus erythematosus. The company collaborates with notable partners including Takeda Pharmaceutical Company, Genentech, Inc., Sanofi, and the Michael J. Fox Foundation, among others, to enhance its research and development efforts. In the financial landscape, the stock is affordable at $13.16 suitable for budget-conscious investors looking to enter the biopharmaceutical market. It has an average trading volume of 1,747,720.00 indicating moderate liquidity, which may appeal to a broad range of investors. With a mid-range market capitalization of $1,924,149,920.00 the company is a steady performer that plays an essential role in the biopharmaceutical industry, contributing significantly to the overall market landscape. Denali Therapeutics belongs to the Healthcare sector, driving innovation and growth, underscoring its commitment to addressing unmet medical needs in neurodegenerative diseases and beyond.
Investing in Denali Therapeutics Inc. (DNLI) depends on multiple factors, including revenue growth, profit margins, debt-to-equity ratio, earnings per share, and return on equity. Analysts have rated it as C+, with a Bearish outlook. Always conduct your own research before investing.
Analysts predict Denali Therapeutics Inc. stock to fluctuate between $10.57 (low) and $33.33 (high) in the next 365 days, reflecting market expectations and potential volatility.
As of 2025-09-15, Denali Therapeutics Inc.'s market cap is $1,924,149,920, based on 146,212,000 outstanding shares.
Compared to Eli Lilly & Co., Denali Therapeutics Inc. has a Lower Market-Cap, indicating a difference in performance.
To buy Denali Therapeutics Inc. (DNLI) stock: Open a brokerage account (e.g., Robinhood, TD Ameritrade, E-Trade). Search for DNLI. Place an order (Market, Limit, etc.).
The best time to invest depends on market trends and technical indicators, which show a Bearish trend based on economic conditions and company performance.
Revenue: $0 | EPS: -$2.57 | Growth: 142.45%.
Visit https://www.denalitherapeutics.com/investor-relations for detailed financial reports.
You can explore historical data from here
All-time high: $56.80 (2021-09-02) | All-time low: $10.57 (2025-04-07).
Key trends include market demand, economic conditions, interest rates, and industry competition, which influence the stock's performance.
News
zacks.com
Denali Therapeutics (DNLI) reported earnings 30 days ago. What's next for the stock?
seekingalpha.com
Denali Therapeutics Inc. (NASDAQ:DNLI ) Morgan Stanley 23rd Annual Global Healthcare Conference September 8, 2025 1:05 PM EDT Company Participants Ryan Watts - Co-Founder, President, CEO & Director Conference Call Participants Sean Laaman - Morgan Stanley, Research Division Presentation Sean Laaman Head of Healthcare Research & Equity Analyst Good afternoon, everyone, and welcome to Morgan Stanley Global Healthcare Conference. I'm Sean Laaman, Head of U.S. mid-cap biotech equity research at the firm.
zacks.com
Denali Therapeutics posts narrower-than-expected Q2 loss. The company advances multiple rare disease therapies toward potential approvals.
zacks.com
Denali's lead drug for Hunter syndrome wins FDA Priority Review, marking a key step toward commercial-stage status.
zacks.com
Denali Therapeutics (DNLI) reported earnings 30 days ago. What's next for the stock?
zacks.com
DNLI reports a wider-than-expected loss for the first quarter of 2025. Denali submits a BLA for tividenofusp alfa under the FDA?
zacks.com
Denali stock up as it begins rolling BLA submission with the FDA for accelerated approval of tividenofusp alfa for the treatment of Hunter syndrome.
zacks.com
DNLI reports a narrower-than-expected loss for the fourth quarter of 2024. Denali remains on track to submit a BLA for tividenofusp alfa for the treatment of MPS II (Hunter syndrome).
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